At Ostendum, we are developing the next generation of medical diagnostics equipment. With our lab-on-a-chip technology, we offer a fast and highly sensitive, portable biosensor for the detection of bacteria, viruses, yeasts, and biomarkers. With hightech optical chips and a portable detector, we enable point of care testing for better diagnostics at lower cost.
Baked in the cleanrooms of the University of Twente, our optical chips make use of the latest advances in nanotechnology. Optical waveguides are constructed on silicon wafers, with features at the nanometer scale. Multiple optical pathways per chip enable parallel detection of multiple analytes, relative to one or more dedicated reference channels. An on-chip interferometer mixes the optical waves from each measurement channel with the references, resulting in a continuous measurement of the analytes in the sample.
Along the optical paths of each chip, sensing windows are etched into the surface, in which specific antibodies for each analyte are chemically bound. Upon exposure to a sample of blood, saliva, milk, or urine; the antibody-analyte binding process is followed in real-time by our detector. We do not merely detect the presence of the analyte, but we also quantify the concentration. Within minutes, you get an accurate read-out of the concentration of antigens, bacteria, or virus particles in whole blood samples (or any other fluid).
Ostendum has opted for Scienion’s SX high speed precision spotter to pre-coat its chips in house. This enables high throughput production and excellent reproducibility. Test kits require no further pre-treatment by the operator: just apply your sample and wait for the results.